Which medication is used to treat miscarriage?

• A. Dinoprostone
• B. Misoprostol
• C. Mifepristone
• D. Methotrexate

Answer: (B)

Medical management of miscarriage relies on a drug that makes the uterus contract to expel tissue. Misoprostol is used for this purpose because it reliably induces uterine contractions and cervical ripening, allowing the products of conception to be expelled without surgery. It can be given by several routes and often used in outpatient settings, offering a safe, effective option for early pregnancy loss. While dinoprostone can also induce abortion or cervical change, misoprostol has the strongest evidence base and versatile dosing for managing miscarriage. Mifepristone is mainly used to start a medical abortion in combination with misoprostol, not by itself for miscarriage. Methotrexate is typically reserved for ectopic pregnancies and some abortion regimens, not standard for intrauterine miscarriage.