Which of the following is NOT a monophasic COC formulation?

Prepare for the NAPLEX Contraception and Infertility Test. Engage with interactive flashcards and multiple choice questions, each equipped with hints and explanations. Ensure your readiness for the exam!

Multiple Choice

Which of the following is NOT a monophasic COC formulation?

The main concept is monophasic versus multiphasic combined oral contraceptives. Monophasic pills deliver the same amount of estrogen and progestin in every active pill, so hormone levels remain constant throughout the 21 active days (followed by placebo or a pill-free interval). Triphasic or multiphasic formulations change the hormone doses across different weeks to more closely mimic the natural cycle. Tri-Sprintec is a triphasic product, meaning the active pills contain three different hormone dose combinations across the cycle. The other options—Sprintec 28, Loestrin 1/20, and Yasmin 28—provide identical hormone content in each active pill, making them monophasic. Therefore Tri-Sprintec is not monophasic.

The main concept is monophasic versus multiphasic combined oral contraceptives. Monophasic pills deliver the same amount of estrogen and progestin in every active pill, so hormone levels remain constant throughout the 21 active days (followed by placebo or a pill-free interval). Triphasic or multiphasic formulations change the hormone doses across different weeks to more closely mimic the natural cycle.

Tri-Sprintec is a triphasic product, meaning the active pills contain three different hormone dose combinations across the cycle. The other options—Sprintec 28, Loestrin 1/20, and Yasmin 28—provide identical hormone content in each active pill, making them monophasic. Therefore Tri-Sprintec is not monophasic.

More practice questions