Which progestin is listed as having lower androgenic activity and used to address acne or hirsutism?

• A. Norgestimate
• B. Ethynodiol diacetate
• C. Desogestrel
• D. Levonorgestrel

Answer: (A)

Lower androgenic activity among progestins helps reduce androgen-driven acne and hirsutism, so a progestin with a minimal androgen effect is preferred for these conditions. Norgestimate is a third-generation progestin with notably low intrinsic androgenic activity compared with older progestins. When used in combined oral contraceptives, it provides contraception with less androgenic influence on the skin and hair, helping address acne or hirsutism. Other options listed have higher androgenic activity, making them less ideal for acne/hirsutism management.