Which statement best describes the 'freeze-all' approach?

• A. It uses clomiphene to trigger ovulation
• B. It increases OHSS risk
• C. It is the same as a fresh transfer protocol
• D. It defers embryo transfer to a later cycle to reduce OHSS risk.

Answer: (D)

The main idea here is that the freeze-all approach separates the embryo transfer from the stimulated cycle to lower the risk of ovarian hyperstimulation syndrome. After egg retrieval, all viable embryos are frozen, and transfer is performed in a later cycle when the body is not under the same high hormonal stress. This postponement reduces the likelihood of OHSS because pregnancy in a highly stimulated cycle can worsen that risk. It’s not about using clomiphene to trigger ovulation, and it isn’t the same as a fresh transfer protocol since the embryo transfer happens later. Additionally, this approach actually decreases OHSS risk, not increases it.